Thrombosis prevention after total hip and kneereplacement: What are the advantages or disadvantages of apixaban (Eliquis)?
Apixaban (Eliquis trading name) is authorized since May 2011 for the prevention of thrombosis after kneereplacement surgery to replace a hip or knee joint.
After the insertion of an artificial hip or knee joint is increased in the blood vessels for a time the risk of clots. These clots (medical: thrombus) may then be washed away with the blood flow and block at another location in the body of a blood vessel. Most clots but are metabolized by the body so quickly that they do not cause any discomfort. Sometimes, however, occur in the weeks following joint replacement surgery symptomatic "thromboembolism," for example in the lungs and inside of the leg arterial system (known as deep vein). For prevention of thrombosis, leading to discomfort, there are several medications available. With apixaban in May 2011, another product has been authorized. How is apixaban?
Apixaban is taken twice daily as a tablet (2.5 mg), the first time. Within 12 to 24 hours after kneereplacement surgery After a hip replacement, it should be taken 32 to 38 days after a kneereplacement 10 to 14 days.