I'm a 43 yr old female who was diagnosed with severe rheumatoid arthritis 10 yrs ago. I have been on different medications to help control my inflammation. One medicine that helps best is prednisone. I've been on/off it throughout the years. My most recent dose was 20mg that started August 2015 and I just weened off about a month ago. Long story short, I have little to no cartilage in both knees and was told I would need a total knee replacement in both knees. I'm to ths point were I am no longer able to work and assistance getting in/out of bed, going to the restroom, or doing anything else for that matter. I would like advice on what I should do next. I'm in constant pain and cortisone shots are ineffective.